WEB-based GEne SeT AnaLysis Toolkit
 
Translating gene lists into biological insights...
 


User data and parameters: User data: textAreaUpload.txt, Organism: hsapiens, Id Type: ensembl_gene_stable_id, Ref Set: entrezgene, Significance Level: Top10, Statistics Test: Hypergeometric, MTC: BH, Minimum: 2

The results for each enriched gene sets are listed in this table.
For each gene set, the first row lists database name, gene set name , and corresponding gene set ID. The second row lists the following statistics:
Finally, genes in the gene set are listed. For each gene, the table lists the user uploaded ID and value (optional), Entrez ID, Ensembl Gene Stable ID, Gene symbol, and description. Ensembl Gene Stable ID and Entrez Gene ID are linked to the Ensembl and Entrez Gene databases, respectively.

Database:Transcription Target       Name:hsa_V$YY1_Q6       ID:DB_ID:2268
C=238; O=6; E=0.30; R=19.77; rawP=6.13e-07; adjP=4.03e-05
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000197102 NA DYNC1H1 dynein, cytoplasmic 1, heavy chain 1 1778 ENSG00000197102
2  ENSG00000100393 NA EP300 E1A binding protein p300 2033 ENSG00000100393
3  ENSG00000176994 NA SMCR8 Smith-Magenis syndrome chromosome region, candidate 8 140775 ENSG00000176994
4  ENSG00000184677 NA ZBTB40 zinc finger and BTB domain containing 40 9923 ENSG00000184677
5  ENSG00000074755 NA ZZEF1 zinc finger, ZZ-type with EF-hand domain 1 23140 ENSG00000074755
6  ENSG00000132405 NA TBC1D14 TBC1 domain family, member 14 57533 ENSG00000132405


Database:Transcription Target       Name:hsa_RRAGTTGT_UNKNOWN       ID:DB_ID:2351
C=248; O=6; E=0.32; R=18.97; rawP=7.79e-07; adjP=4.03e-05
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000088812 NA ATRN attractin 8455 ENSG00000088812
2  ENSG00000167548 NA MLL2 myeloid/lymphoid or mixed-lineage leukemia 2 8085 ENSG00000167548
3  ENSG00000176994 NA SMCR8 Smith-Magenis syndrome chromosome region, candidate 8 140775 ENSG00000176994
4  ENSG00000132694 NA ARHGEF11 Rho guanine nucleotide exchange factor (GEF) 11 9826 ENSG00000132694
5  ENSG00000082805 NA ERC1 ELKS/RAB6-interacting/CAST family member 1 23085 ENSG00000082805
6  ENSG00000049618 NA ARID1B AT rich interactive domain 1B (SWI1-like) 57492 ENSG00000049618


Database:Transcription Target       Name:hsa_GCCATNTTG_V$YY1_Q6       ID:DB_ID:2459
C=419; O=7; E=0.53; R=13.10; rawP=1.06e-06; adjP=4.03e-05
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000197102 NA DYNC1H1 dynein, cytoplasmic 1, heavy chain 1 1778 ENSG00000197102
2  ENSG00000100393 NA EP300 E1A binding protein p300 2033 ENSG00000100393
3  ENSG00000155034 NA FBXL18 F-box and leucine-rich repeat protein 18 80028 ENSG00000155034
4  ENSG00000176994 NA SMCR8 Smith-Magenis syndrome chromosome region, candidate 8 140775 ENSG00000176994
5  ENSG00000184677 NA ZBTB40 zinc finger and BTB domain containing 40 9923 ENSG00000184677
6  ENSG00000132405 NA TBC1D14 TBC1 domain family, member 14 57533 ENSG00000132405
7  ENSG00000188612 NA SUMO2 SMT3 suppressor of mif two 3 homolog 2 (S. cerevisiae) 6613 ENSG00000188612


Database:Transcription Target       Name:hsa_V$YY1_02       ID:DB_ID:1886
C=239; O=5; E=0.30; R=16.40; rawP=1.39e-05; adjP=0.0004
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000100393 NA EP300 E1A binding protein p300 2033 ENSG00000100393
2  ENSG00000176994 NA SMCR8 Smith-Magenis syndrome chromosome region, candidate 8 140775 ENSG00000176994
3  ENSG00000184677 NA ZBTB40 zinc finger and BTB domain containing 40 9923 ENSG00000184677
4  ENSG00000074755 NA ZZEF1 zinc finger, ZZ-type with EF-hand domain 1 23140 ENSG00000074755
5  ENSG00000132405 NA TBC1D14 TBC1 domain family, member 14 57533 ENSG00000132405


Database:Transcription Target       Name:hsa_V$CREBP1_01       ID:DB_ID:1866
C=175; O=4; E=0.22; R=17.92; rawP=7.60e-05; adjP=0.0017
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000100393 NA EP300 E1A binding protein p300 2033 ENSG00000100393
2  ENSG00000124942 NA AHNAK AHNAK nucleoprotein 79026 ENSG00000124942
3  ENSG00000049618 NA ARID1B AT rich interactive domain 1B (SWI1-like) 57492 ENSG00000049618
4  ENSG00000076067 NA RBMS2 RNA binding motif, single stranded interacting protein 2 5939 ENSG00000076067


Database:Transcription Target       Name:hsa_V$ARNT_02       ID:DB_ID:2166
C=244; O=4; E=0.31; R=12.85; rawP=0.0003; adjP=0.0049
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000197081 NA IGF2R insulin-like growth factor 2 receptor 3482 ENSG00000197081
2  ENSG00000184677 NA ZBTB40 zinc finger and BTB domain containing 40 9923 ENSG00000184677
3  ENSG00000072121 NA ZFYVE26 zinc finger, FYVE domain containing 26 23503 ENSG00000072121
4  ENSG00000127481 NA UBR4 ubiquitin protein ligase E3 component n-recognin 4 23352 ENSG00000127481


Database:Transcription Target       Name:hsa_V$NFMUE1_Q6       ID:DB_ID:2191
C=239; O=4; E=0.30; R=13.12; rawP=0.0003; adjP=0.0049
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000197102 NA DYNC1H1 dynein, cytoplasmic 1, heavy chain 1 1778 ENSG00000197102
2  ENSG00000100393 NA EP300 E1A binding protein p300 2033 ENSG00000100393
3  ENSG00000176994 NA SMCR8 Smith-Magenis syndrome chromosome region, candidate 8 140775 ENSG00000176994
4  ENSG00000074755 NA ZZEF1 zinc finger, ZZ-type with EF-hand domain 1 23140 ENSG00000074755


Database:Transcription Target       Name:hsa_AACTTT_UNKNOWN       ID:DB_ID:1851
C=1859; O=9; E=2.37; R=3.80; rawP=0.0005; adjP=0.0057
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000005339 NA CREBBP CREB binding protein 1387 ENSG00000005339
2  ENSG00000197081 NA IGF2R insulin-like growth factor 2 receptor 3482 ENSG00000197081
3  ENSG00000167548 NA MLL2 myeloid/lymphoid or mixed-lineage leukemia 2 8085 ENSG00000167548
4  ENSG00000132694 NA ARHGEF11 Rho guanine nucleotide exchange factor (GEF) 11 9826 ENSG00000132694
5  ENSG00000188612 NA SUMO2 SMT3 suppressor of mif two 3 homolog 2 (S. cerevisiae) 6613 ENSG00000188612
6  ENSG00000151240 NA DIP2C DIP2 disco-interacting protein 2 homolog C (Drosophila) 22982 ENSG00000151240
7  ENSG00000140548 NA ZNF710 zinc finger protein 710 374655 ENSG00000140548
8  ENSG00000049618 NA ARID1B AT rich interactive domain 1B (SWI1-like) 57492 ENSG00000049618
9  ENSG00000127481 NA UBR4 ubiquitin protein ligase E3 component n-recognin 4 23352 ENSG00000127481


Database:Transcription Target       Name:hsa_AAGWWRNYGGC_UNKNOWN       ID:DB_ID:1884
C=117; O=3; E=0.15; R=20.11; rawP=0.0005; adjP=0.0057
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000198752 NA CDC42BPB CDC42 binding protein kinase beta (DMPK-like) 9578 ENSG00000198752
2  ENSG00000100393 NA EP300 E1A binding protein p300 2033 ENSG00000100393
3  ENSG00000074755 NA ZZEF1 zinc finger, ZZ-type with EF-hand domain 1 23140 ENSG00000074755


Database:Transcription Target       Name:hsa_V$IK2_01       ID:DB_ID:1903
C=265; O=4; E=0.34; R=11.84; rawP=0.0004; adjP=0.0057
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000124942 NA AHNAK AHNAK nucleoprotein 79026 ENSG00000124942
2  ENSG00000151067 NA CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit 775 ENSG00000151067
3  ENSG00000082805 NA ERC1 ELKS/RAB6-interacting/CAST family member 1 23085 ENSG00000082805
4  ENSG00000076067 NA RBMS2 RNA binding motif, single stranded interacting protein 2 5939 ENSG00000076067




WebGestalt is currently developed and maintained by Jing Wang and Bing Zhang at the Zhang Lab. Other people who have made significant contribution to the project include Dexter Duncan, Stefan Kirov, Zhiao Shi, and Jay Snoddy.

Funding credits: NIH/NIAAA (U01 AA016662, U01 AA013512); NIH/NIDA (P01 DA015027); NIH/NIMH (P50 MH078028, P50 MH096972); NIH/NCI (U24 CA159988); NIH/NIGMS (R01 GM088822).